
DEFY THE
WAIT.
TOGETHER.
DEFY THE
WAIT.
TOGETHER.
Defiant owns the peri-diagnostic period — so your members get answers in days, not months, and start on the right treatment the first time.
THE PROBLEM
The peri-diagnostic period is where cancer care goes wrong.
118 days
Median time from first symptom to a cancer diagnosis — about four months of waiting.
Gitlin et al., JMCSP 2023
1 in 5
Patients may begin on the wrong treatment — costly in dollars, and in outcomes.
WSJ / MD Anderson, 2024
100%
Higher cost for infused drugs in hospital outpatient vs. the physician office.
Robinson, Health Affairs 2021
WHAT DEFIANT DOES
One journey, owned end to end.
Suspicion
ENGAGE
We reach the right member at the right moment — triggered by signals you already have: eligibility, prior authorization, labs.
Diagnosis
ACCELERATE
Supply aggregation, parallel test ordering, and coordinated logistics collapse the diagnosis timeline from months to days.
Right Doctor
NAVIGATE
Quality- and fit-based oncologist matching: community-first when appropriate, an academic center or trial when complexity demands it.
Treatment
INFLUENCE
Community care aligned to Dana-Farber standards through pre-staged tests and care-plan review.
how we help
We enhance the value of every cancer strategy.
Defiant enhances the ROI of care navigation, COE programs, and screening — by handing them better-prepared patients, faster.
Suspicion
Diagnosis
Right Doctor
Treatment
Defiant — The peri-diagnostic period
Screening programs
Care navigation
Center of excellence
Second opinion
Suspicion
Diagnosis
Right Doctor
Treatment
Defiant — The peri-diagnostic period
Screening programs
Care navigation
For plans with ThymeCare or Atlas, Defiant helps navigate more patients to partner practices.
Center of excellence
Improved engagement with Center of Excellence programs
Second opinion
Targeted engagement of second opinion improved return on investment.
who we partner with
One program, three front doors.
HEALTH PLANS
Community providers, Dana-Farber quality care.
Defiant accelerates your members’ diagnostic journey by up to 90% and gives them the confidence to get the best care close to home.
Data driven outreach engages members when they need it most
Answers in days, not months
Concierge level navigation
Oncologist collaboration driven by Dana-Farber Care Intelligence
Employers
The cancer benefit that actually shows up.
When an employee hears 'it might be cancer,' Defiant is there within days — answers, a plan, someone to call. Nothing for your team to manage.
Proactive outreach that reaches employees the moment a diagnosis is in question
Diagnostic answers in days, not months
A guide through every appointment
Local care, backed by Dana-Farber Care Intelligence
RISK-BEARING PROVIDER GROUPS
Keep the patient.
Skip the load.
Skip the load.
One referral puts our team to work on the diagnostic window. Your patient gets answers in days, you keep the relationship — and the cost of delay comes off your books.
One-touch oncologist-to-oncologist referral
Your patients get answers in days, not months
A dedicated guide for every patient, from first scan to treatment plan
Community-based care, backed by Dana-Farber Care Intelligence
Who WE ARE
Co-founded by Dana-Farber Cancer Institute
Defiant Health was co-founded by a global leader in cancer care.
Dana-Farber Cancer Institute is a Harvard Medical School teaching affiliate and National Cancer Institute-designated Comprehensive Cancer Center, recognized globally for cutting-edge cancer research and compassionate clinical care.
This partnership leverages Dana-Farber's leading clinical standards and brings that expertise directly to your care with Defiant—ultimately working to advance Dana-Farber’s mission to make world-class cancer care accessible to all patients, wherever they are. All clinical services are provided by Defiant Health and its partners.
This partnership leverages Dana-Farber's leading clinical standards and brings that expertise directly to your care with Defiant—ultimately working to advance Dana-Farber’s mission to make world-class cancer care accessible to all patients, wherever they are. All clinical services are provided by Defiant Health and its partners.

OUR RESULTS
What the Boston pilot showed — where your patients get treated matters.
These stories and statistics are from our breast cancer patients in Boston — where diagnostic delays are some of the worst in healthcare. The methods we built there now move every Defiant patient through faster, whatever their cancer.
CLARITY
Every cancer diagnosis deserves answers in days, not months — with the right plan, the right doctors, and Dana-Farber behind every step.
Talk to our teamStarts
Here
Every cancer diagnosis deserves answers in days, not months — backed by Dana-Farber's clinical intelligence. Defiant is how you get there.
Talk to our team
